Publication summary

This paper analyses the methodological approaches to estimating the global burden of disease due to antimicrobial resistance. The task of estimating the global burden of disease (GBD) due to infections caused by resistant pathogens is crucial to provide evidence to guide action and direct resource allocation. Two lead attempts at estimating the GBD for antimicrobial resistance (AMR) have been made; the O’Neill review and the GBD 2016 study. The methodological approaches of the two studies are analysed further in this study.

Who this is for

  • Mathematicians/Statisticians
  • Policymakers
  • Epidemiologists
  • Diagnostic and medical device professionals

Key findings

  • Estimation of deaths caused by AMR should be prioritised overuse of attributable or all-cause mortality only.
  • There is a need to strengthen the approach for recording and estimating deaths due to AMR.
  • Innovative tools and strategies to maximise data collection are needed to support accurate assessment of burden of disease